Will generate a trajectory using STEMNET.

This method was wrapped inside a container. The original code of this method is available here.

ti_stemnet(alpha = 0.1, lambda_auto = TRUE, lambda = 0.1,
  force = FALSE, run_environment = NULL)

Arguments

alpha

numeric; The elastic net mixing parameter of the ‘glmnet’ classifier. (default: 0.1; range: from 0.001 to 10L)

lambda_auto

logical; Whether to select the lambda by cross-validation

lambda

numeric; The lambda penalty of GLM. (default: 0.1; range: from 0.05 to 1L)

force

logical; Do not use! This is a parameter to force FateID to run on benchmark datasets where not enough end groups are present.

run_environment

In which environment to run the method, can be "docker" or "singularity".

Value

A TI method wrapper to be used together with infer_trajectory

References

Velten, L., Haas, S.F., Raffel, S., Blaszkiewicz, S., Islam, S., Hennig, B.P., Hirche, C., Lutz, C., Buss, E.C., Nowak, D., Boch, T., Hofmann, W.-K., Ho, A.D., Huber, W., Trumpp, A., Essers, M.A.G., Steinmetz, L.M., 2017. Human haematopoietic stem cell lineage commitment is a continuous process. Nature Cell Biology 19, 271–281.