Will generate a trajectory using cellTree with gibbs.

This method was wrapped inside a container. The original code of this method is available here.

ti_celltree_gibbs(method = "Gibbs", sd_filter = 0.5,
  absolute_width = 0, width_scale_factor = 1.5,
  outlier_tolerance_factor = 0.1, rooting_method = "null",
  num_topics = 4, tot_iter = 200L, tolerance = 1e-05,
  run_environment = NULL)

Arguments

method

discrete; (default: "Gibbs"; values: "Gibbs")

sd_filter

numeric; (default: 0.5; range: from 0.01 to 5)

absolute_width

numeric; (default: 0; range: from NULL to NULL)

width_scale_factor

numeric; (default: 1.5; range: from 0.1 to 100)

outlier_tolerance_factor

numeric; (default: 0.1; range: from 1e-04 to 1000)

rooting_method

discrete; (default: "null"; values: "longest.path", "center.start.group", "average.start.group", "null")

num_topics

integer; (default: 4; range: from 2 to 15)

tot_iter

numeric; (default: 200L; range: from 10L to 1000L)

tolerance

numeric; (default: 1e-05; range: from 1e-07 to 0.001)

run_environment

In which environment to run the method, can be "docker" or "singularity".

Value

A TI method wrapper to be used together with infer_trajectory

References

duVerle, D.A., Yotsukura, S., Nomura, S., Aburatani, H., Tsuda, K., 2016. CellTree: an R/bioconductor package to infer the hierarchical structure of cell populations from single-cell RNA-seq data. BMC Bioinformatics 17.