For example, what are the start cells, the end cells, to which milestone does each cell belong to.

generate_prior_information(cell_ids, milestone_ids, milestone_network,
  milestone_percentages, progressions, divergence_regions, expression,
  feature_info = NULL, cell_info = NULL, marker_fdr = 0.005)

Arguments

cell_ids

The ids of the cells.

milestone_ids

The ids of the milestones in the trajectory. Type: Character vector.

milestone_network

The network of the milestones. Type: Data frame(from = character, to = character, length = numeric, directed = logical).

milestone_percentages

A data frame specifying what percentage milestone each cell consists of. Type: Data frame(cell_id = character, milestone_id = character, percentage = numeric).

progressions

Specifies the progression of a cell along a transition in the milestone_network. Type: Data frame(cell_id = character, from = character, to = character, percentage = numeric).

divergence_regions

A data frame specifying the divergence regions between milestones (e.g. a bifurcation). Type: Data frame(divergence_id = character, milestone_id = character, is_start = logical).

expression

The normalised expression values with genes in columns and cells in rows

feature_info

Optional meta-information of the features, a data.frame with at least feature_id as column

cell_info

Optional meta-information pertaining the cells.

marker_fdr

Maximal FDR value for a gene to be considered a marker