R/wrap_add_prior_information.R
generate_prior_information.Rd
For example, what are the start cells, the end cells, to which milestone does each cell belong to.
generate_prior_information(cell_ids, milestone_ids, milestone_network, milestone_percentages, progressions, divergence_regions, expression, feature_info = NULL, cell_info = NULL, marker_fdr = 0.005)
cell_ids | The ids of the cells. |
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milestone_ids | The ids of the milestones in the trajectory. Type: Character vector. |
milestone_network | The network of the milestones. Type: Data frame(from = character, to = character, length = numeric, directed = logical). |
milestone_percentages | A data frame specifying what percentage milestone each cell consists of. Type: Data frame(cell_id = character, milestone_id = character, percentage = numeric). |
progressions | Specifies the progression of a cell along a transition in the milestone_network. Type: Data frame(cell_id = character, from = character, to = character, percentage = numeric). |
divergence_regions | A data frame specifying the divergence regions between milestones (e.g. a bifurcation). Type: Data frame(divergence_id = character, milestone_id = character, is_start = logical). |
expression | The normalised expression values with genes in columns and cells in rows |
feature_info | Optional meta-information of the features, a data.frame with at least feature_id as column |
cell_info | Optional meta-information pertaining the cells. |
marker_fdr | Maximal FDR value for a gene to be considered a marker |